Pogenic granuloma in children (literature review and own research data)
DOI:
https://doi.org/10.15574/PS.2021.70.45Keywords:
pyogenic granuloma, children, neoplasmsAbstract
Pyogenic granuloma is a benign vascular formation that occurs as a result of the process of impaired wound healing in combination with vascular proliferation, and which can be regarded as a reactive process. Histologically, pyogenic granuloma is characterized by the growth of granulation tissue with a large number of dilated, swollen capillary endothelium, swollen stroma, sometimes containing an inflammatory infiltrate consisting of lymphocytes, neutrophils, plasma cells and fibroblasts among the loose connective tissue. Exophytic lobular proliferation of capillaries is well expressed, the epidermis is sometimes eroded with peripheral epidermal layers and areas of acanthosis on the periphery.
For the last 5 years, in the period from 2015 to 2020, 18 patients with a diagnosis of pyogenic granuloma were hospitalized at the pediatric surgery Clinic of the Vinnytsia National Pirogov Memorial Medical University (Ukraine). The average age of patients was 8.98±0.97 years old. According to the obtained data, the maximum number of patients was in the range of 5–13 years, which coincides with the results of other researchers. Regarding the localization of pyogenic granuloma among all patients of the general study group, it was distributed as follows: head-neck – 14 patients, upper torso – 3 cases and in 1 child a pyogenic tumor was located on the finger. All children underwent surgical removal of pyogenic granuloma within healthy tissues. Complications and recurrences of the disease were not observed in any clinical case.
Pediatricians should pay attention to the presence of tumors, especially those that have occurred at the site of injury, even minor, in order to exclude more complex pathology, such as melanoma.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of these Institutes. The informed consent of the patient was obtained for conducting the studies.
The authors declare no conflicts of interests.
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