Experience in the treatment of early neonatal parasitic sepsis in the maternity hospital

Abstract

Early neonatal sepsis mainly has bacterial etiology – 84%, less often fungal – 12%, otherwise – viral and parasitic etiology. According to the European Center for Disease Control and Prevention (CDC), the occurrence of sepsis in newborns is closely related to birth weight and gestational age, as well as skin color. It was established, in particular, that the most severe types of sepsis occur in children weighing 400–1500 g at birth and less than 30 weeks of gestation. Parasitic sepsis in newborns refers to severe forms of childhood sepsis, with mortality reaching high. The article presents the experience of successful treatment of 2 newborns in a maternity hospital both were non-transportable. At the beginning of treatment, the anamnesis of pregnancy was thoroughly studied. From the first day of the disease, both patients underwent a comprehensive instrumental (ultrasound, X-ray) and laboratory (PCR, ELISA, procalcitonin, coagulogram, CRP and general biochemistry tests) examinations. One child – prematurely born at 30 weeks of gestation with a weight of 1070 grams – was treated for intrauterine chlamydial sepsis. The second suffered from intrauterine toxoplasmotic sepsis and Rhconflict; the latter was treated in utero at 30 weeks of gestation. Both patients were treated by a multidisciplinary team and the children recovered.

Conclusions. The results of treatment show effectiveness pathogen approach to the treatment of severe sepsis in newborns.

The research was carried out in accordance with the principles of the Declaration of Helsinki. The permission of the parents of the children was obtained to conduct the research.

The authors declare no conflicts of interest.