The treatment strategy for giant neck teratoma in newborns: clinical case
DOI:
https://doi.org/10.15574/PS.2024.83.107Keywords:
teratoma, newborn child, surgical interventionAbstract
Teratoma can be diagnosed with ultrasound examination and screening, which is carried out in intrauterine period of the fetal development. Early diagnostics of the pathology is of the great importance of its treatment. The detailed management of newborns with giant neck teratoma have not been found in current literature. Furthermore, there is no information concerning preparation of the patient for the radical operation.
The aim is to present the clinical case of surgical treatment of giant neck teratoma in newborn child using EXIT-procedure (intrauterine treatment to establish a functioning airway) and angiography before the radical excision of the tumor.
The clinical case describes the diagnostics and treatment of newborn child with giant neck teratoma, who was taken to the first clinical Lviv association “St. Nicholas hospital”. The tumor was diagnosed intrauterine. The child underwent EXIT-procedure. Selective angiography and embolization of carotid branches were carried out on third day after birth. The surgical intervention regarding the removal of the tumor, which was removed radically with blood loss up to 50 ml, was performed on fourth day after birth.
Conclusions. Prenatal screening with alpha-protein detection in mother blood is essential for diagnostics of probable pathologies of the fetal development. EXIT-procedure has led to save lung ventilation and effective support of the cardiovascular system. The selective angiography allowed to assess the bloodstream within branches of the internal carotid artery. The embolization of the branches of the external carotid artery, which vascularized the tumor, led to minimization of the blood loss up to 50 ml. As the removal of tumor was radical, further specialized treatment was not needed.
The research was carried out in accordance to principles of the Helsinki declaration. The informed consent of the child’s parents was given for conducting the research.
The authors declare no conflict of interest.
References
Arlikar JD, Mane SB, Dhende NP, Sanghavi Y, Valand AG, Butale PR. (2009, Mar). Fetus in fetu: two case reports and review of literature. Pediatric Surgery International. 25(3): 289-292. https://doi.org/10.1007/s00383-009-2328-8; PMid:19184054
Blum B, Benvenisty N. (2008). The tumorigenicity of human embryonic stem cells. Adv Cancer Res. 100: 133-58. https://doi.org/10.1016/S0065-230X(08)00005-5; PMid:18620095
Joshi D, Stellon M, Antony K, Beninati M, Luks FI, Puricelli M, Lobeck IN. (2023). Indications, Resource Allocation, and Outcomes Associated with Ex-Utero Intrapartum Treatment Procedures: A North American Fetal Therapy Network Survey. Fetal Diagn Ther. 50(5): 376-386. https://doi.org/10.1159/000531615; PMid:37339615 PMCid:PMC10614236
Mohta A, Khurana N. (2011, Apr 5). Fetus-In-Fetu or Well-Differentiated Teratoma - A Continued Controversy. Indian Journal of Surgery. 73(5): 372-374. ISSN 0972-2068. https://doi.org/10.1007/s12262-011-0251-4; PMid:23024547 PMCid:PMC3208714
Mosquera MS, Yuter S, Flake AW. (2023, Oct). Perinatal management of the anticipated difficult airway. Semin Fetal Neonatal Med. 28(5): 101485. https://doi.org/10.1016/j.siny.2023.101485; PMid:38030438
Oré Acevedo JF, Ventura Laveriano W, Alvarado Zelada J. (2023, Jan-Feb). Case report: EXIT procedure in cervical teratoma during pregnancy. Acta Otorrinolaringol Esp (Engl Ed). 74(1): 59-62. https://doi.org/10.1016/j.otoeng.2023.01.001; PMid:36708991
Peiro JL, Sbragia L, Scorletti F, Lim FY, Shaaban A. (2016 Jul). Management of fetal teratomas. Pediatr Surg Int. 32 (7): 635647. https://doi.org/10.1007/s00383-016-3892-3; PMid:27112491
Sung S, Mahdy H. (2023). StatPearls [Internet]. StatPearls Publishing; Treasure Island (FL): Jul 9, 2023. Cesarean Section.
Uri B-D, Nissim B. (2011, Mar 10). The tumorigenicity of human embryonic and induced pluripotent stem cells. Nature Reviews Cancer. 11(4): 268-277. ISSN 1474-175X. https://doi.org/10.1038/nrc3034; PMid:21390058
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Paediatric Surgery (Ukraine)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The policy of the Journal “PAEDIATRIC SURGERY. UKRAINE” is compatible with the vast majority of funders' of open access and self-archiving policies. The journal provides immediate open access route being convinced that everyone – not only scientists - can benefit from research results, and publishes articles exclusively under open access distribution, with a Creative Commons Attribution-Noncommercial 4.0 international license(СС BY-NC).
Authors transfer the copyright to the Journal “PAEDIATRIC SURGERY.UKRAINE” when the manuscript is accepted for publication. Authors declare that this manuscript has not been published nor is under simultaneous consideration for publication elsewhere. After publication, the articles become freely available on-line to the public.
Readers have the right to use, distribute, and reproduce articles in any medium, provided the articles and the journal are properly cited.
The use of published materials for commercial purposes is strongly prohibited.
