A clinical case of tuberculous rib damage as an etiological cause of chest neoplasm in an early age child

Authors

DOI:

https://doi.org/10.15574/PS.2024.4(85).130135

Keywords:

rib, tuberculosis, diagnosis, surgical treatment, children

Abstract

Extrapulmonary tuberculosis is as one of the etiological causes of chest neoplasms in early age children, which does not have marker risk factors for its induction in the human body and specific symptoms. This leads to a significant amount case of hypodiagnosis and the choice of wrong treatment tactics by a pediatric surgeon.

Aim - to analyze the causes of untimely diagnosis and the peculiarities of the diagnostic and therapeutic tactics of neoplasms of tuberculous etiology on the example of a clinical case from one's own practice.

The clinical case is presented the diagnostic and treatment tactic in a patient aged 1 year 3 months with a chest neoplasm of tuberculous genesis, the analysis of which made it possible to determine the reasons for untimely diagnosis and incorrect treatment tactics at the initial stage. The need for a multimodal imaging approach to chest neoplasms, in order to determine its etiology and possible changes in other organs, is presented and substantiated. The effectiveness of complex laboratory diagnostics, which includes molecular genetic research methods, in the case of suspected tuberculous etiology of the inflammatory process, was determined. The possible options and volume of surgical resection of the rib in the case of tuberculous destruction were analyzed.

The research was carried out in accordance with the principles of the Declaration of Helsinki. Parents' informed consent was obtained for children's participation in the study.

The authors declare no conflict of interest.

References

Agashe VM, Johari AN, Shah M, Anjum R, Romano C, Drago L et al. (2020). Diagnosis of Osteoarticular tuberculosis: Perceptions, protocols, practices, and priorities in the Endemic and Non-Endemic Areas of the World - A WAIOT View. Microorganisms. 8(9): 1312. https://doi.org/10.3390/microorganisms8091312; PMid:32872175 PMCid:PMC7563388

Bertrand KJ, Rose N, Franck L, Célestin B, Ibrahim T, Constance BN. (2022). Mastitis and breast abscess in newborns and infants. African Journal of Paediatric Surgery. 19(4): 238. https://doi.org/10.4103/ajps.ajps_92_21; PMid:36018205 PMCid:PMC9615954

Chang JH, Kim SK, Lee WY. (1999). Diagnostic issues in tuberculosis of the ribs with a review of 12 surgically proven cases. Respirology. 4(3): 249-253. https://doi.org/10.1046/j.1440-1843.1999.00183.x; PMid:10489667

Chaweephisal P, Torchareon T, Shuangshoti S, Techavichit P. (2020). Chest wall Mass in Infancy: The presentation of Bone-Tumor-Like BCG Osteitis. Case Reports in Pediatrics. 2020: 1-5. https://doi.org/10.1155/2020/8884770; PMid:33425419 PMCid:PMC7780224

Chen X, Li R, Ge S, Li Y, Cai C, Weng T et al. (2023). Rapid detection of extensive drug resistance by Xpert MTB/XDR optimizes therapeutic Decision-Making in Rifampin-Resistant tuberculosis patients. Journal of Clinical Microbiology. 61(6). https://doi.org/10.1128/jcm.01832-22; PMid:37249422 PMCid:PMC10281159

Doležalová K, Kika V, Göpfertová D, Wallenfels J. (2022). Trends in incidence of extrapulmonary tuberculosis in children in the Czech Republic in the past 35 years. Central European Journal of Public Health. 30(4): 207-212. https://doi.org/10.21101/cejph.a7499; PMid:36718921

Held MFG, Hoppe S, Laubscher M, Mears S, Dix-Peek S et al. (2017). Epidemiology of Musculoskeletal Tuberculosis in an Area with High Disease Prevalence. Asian Spine Journal. 11(3): 405-411. https://doi.org/10.4184/asj.2017.11.3.405; PMid:28670408 PMCid:PMC5481595

Kashyap NK, Jindal A, Borkar NK, Wasnik M. (2017). Primary tuberculotic osteomyelitis of Rib in a child. Journal of clinical and diagnostic research. 11(7):PD08-PD09. Epub 2017 Jul 1. https://doi.org/10.7860/JCDR/2017/25974.10222; PMid:28892970 PMCid:PMC5583877

Li L, Lv Y, Su L, Liu Q, Lan K, Wei D et al. (2022). Epidemiology of extrapulmonary tuberculosis in central Guangxi from 2016 to 2021. European Journal of Clinical Microbiology & Infectious Diseases. 42(2): 129-140. https://doi.org/10.1007/s10096-022-04524-2; PMid:36445622

Ministry of Health of Ukraine. (2019). On the approval of the Instructions for microbiological diagnosis of tuberculosis. Order of the Ministry of Health of Ukraine June 27. 2019 No. 1462. URL: https://zakon.rada.gov.ua/laws/show/z0886-19/ed20190627#Text.

Olarinoye-Akorede SA, Ibinaiye PO, Suleiman LB. (2020). Ultrasonographic review of pediatric breast masses among Nigerian children in a tertiary hospital. African Journal of Paediatric Surgery. 17(3): 54. https://doi.org/10.4103/ajps.AJPS_57_17; PMid:33342834 PMCid:PMC8051630

Swarup MS, Bhatt S, Rawal R, Tandon A, Dangwal S. (2020). Tuberculosis, a great masquerader: A case series unveiling rare sites of musculoskeletal involvement through imaging. South African Journal of Radiology. 24(1). https://doi.org/10.4102/sajr.v24i1.1919; PMid:33101726 PMCid:PMC7564854

Swerdloff RS, Ng JCM. (2023, Jan 6). Gynecomastia: etiology, diagnosis, and treatment. Endotext. NCBI Bookshelf. URL: https://www.ncbi.nlm.nih.gov/books/NBK279105/.

Tanaka S, Aoki M, Nakanishi T, Otake Y, Matsumoto M, Sakurai T et al. (2011). Retrospective case series analysing the clinical data and treatment options of patients with a tubercular abscess of the chest wall. Interactive Cardiovascular and Thoracic Surgery. 14(3): 249-252. https://doi.org/10.1093/icvts/ivr113; PMid:22184463 PMCid:PMC3290365

Published

2024-12-28