High-flow nasal oxygenation as a method of anesthetic management of patients with «difficult airways»: clinical cases

Authors

DOI:

https://doi.org/10.15574/PS.2025.1(86).131136

Keywords:

children, high-flow nasal oxygenation, difficult airways

Abstract

Surgical treatment of children with pathologies of the oral cavity and upper respiratory tract creates difficulties for both the surgeon and the anesthesiologist.

Aim - to show the effectiveness of high-flow nasal oxygenation in preventing hypoxia in patients with "difficult airway" during surgical interventions in the oral cavity.

Clinical cases. Two clinical cases are presented: the first patient with post-traumatic ankylosis of the temporomandibular joint, the second with macroglossia on the background of Beckwith-Wiedemann syndrome, who underwent oral surgery. Given the anatomical features of the patients, classical intubation of the trachea under direct laryngoscopy was impossible for them. Both patients underwent fiberoptic intubation of the trachea under the STRIVE Hi (Spontaneous Respiration Using Intravenous Anesthesia and High-Flow Nasal Oxygen) anesthesia technique. High-flow nasal oxygenation was used as the main method of respiratory support. Despite the long period of hypoventilation and apnea, both patients had normal oxygenation and ventilation parameters (SpO2 99-98%, EtCO2 47-48 mm Hg)

Conclusions. High-flow nasal oxygenation is an effective method of oxygenation and prevention of hypoxia during the anesthetic management of "difficult airways" in children. Earlier onset of desaturation and hypercapnia in children is associated with young age and smaller functional residual lung capacity.

The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patients was obtained for the study.

The authors declare no conflict of interest.

Author Biography

V.R. Mishchuk, CNE of Lviv Regional Council clinical Centre of children’s healthcare

Danylo Halytsky National Medical University, Lviv, Ukraine

References

Drake MG. (2018). High-flow nasal cannula oxygen in adults: an evidence-based assessment. Ann Am Thorac Soc. 15(2): 145-155. https://doi.org/10.1513/AnnalsATS.201707-548FR; PMid:29144160

Fayed M, Maroun W, Patel N, Galusca D. (2023). Apneic oxygenation: a summarized review and stepwise approach. Cureus. 15(12): e50916. https://doi.org/10.7759/cureus.50916

George S, Humphreys S, Williams T et al. (2019). Transnasal Humidified Rapid Insufflation Ventilatory Exchange in children requiring emergent intubation (Kids THRIVE): a protocol for a randomised controlled trial. BMJ Open. 9(2): e025997. https://doi.org/10.1136/bmjopen-2018-025997; PMid:30787094 PMCid:PMC6398737

George S, Wilson M, Humphreys S et al. (2022). Apnoeic oxygenation during paediatric intubation: A systematic review. Front Pediatr. 10: 918148. https://doi.org/10.3389/fped.2022.918148; PMid:36479287 PMCid:PMC9720125

Hermez L, Spence C, Payton M et al. (2019). A physiological study to determine the mechanism of carbon dioxide clearance during apnoea when using transnasal humidified rapid insufflation ventilatory exchange (THRIVE). Anaesthesia. 74(4): 441-449. https://doi.org/10.1111/anae.14541; PMid:30767199 PMCid:PMC6593707

Humphreys S, Lee-Archer P, Reyne G et al. (2017). Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) in children: a randomized controlled trial. Br J Anaesth. 118(2): 232-238. https://doi.org/10.1093/bja/aew401; PMid:28100527

Jaber S, Monnin M, Girard M et al. (2016). Apnoeic oxygenation via high-flow nasal cannula oxygen combined with non-invasive ventilation preoxygenation for intubation in hypoxaemic patients in the intensive care unit: the single-centre, blinded, randomised controlled OPTINIV trial. Intensive Care Med. 42(12): 1877-1887. https://doi.org/10.1007/s00134-016-4588-9; PMid:27730283

Kim EH, Ji SH, Lee JH et al. (2022). Use of high-flow nasal oxygen in spontaneously breathing pediatric patients undergoing tubeless airway surgery A prospective observational study. Medicine (Baltimore). 101(27): e29520. https://doi.org/10.1097/MD.0000000000029520; PMid:35801795 PMCid:PMC9259177

Parke RL, Bloch A, McGuinness SP. (2015). Effect of very-high-flow nasal therapy on airway pressure and end-expiratory lung impedance in healthy volunteers. Respir Care. 60(10): 1397-1403. https://doi.org/10.4187/respcare.04028; PMid:26329355

Parke RL, Eccleston ML, McGuinness SP. (2011). The effects of flow on airway pressure during nasal High-Flow Oxygen therapy. Respir Care. 56(8): 1151-1155. https://doi.org/10.4187/respcare.01106; PMid:21496369

Patel R, Lenczyk M, Hannallah RS, McGil WA. (1994). Age and the onset of desaturation in apnoeic children. Can J Anaesth. 41(9): 771-774. https://doi.org/10.1007/BF03011582; PMid:7954992

Patel A, Nouraei SA. (2015). Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): a physiological method of increasing apnoea time in patients with difficult airways. Anaesthesia. 70(3): 323-329. https://doi.org/10.1111/anae.12923; PMid:25388828 PMCid:PMC4674986

Pratt M, Miller AB. (2016). Apneic oxygenation: a method to prolong the period of safe apnea. AANA J. 84(5): 322-328.

Renda T, Corrado A, Iskandar G et al. (2018). High-flow nasal oxygen therapy in intensive care and anaesthesia. Br J Anaesth. 120(1): 18-27. https://doi.org/10.1016/j.bja.2017.11.010; PMid:29397127

Published

2025-03-28