The role of transabdominal ultrasound examination in the diagnosis of acute calculous cholecystitis

Authors

DOI:

https://doi.org/10.15574/PS.2025.3(88).7681

Keywords:

acute calculous cholecystitis, ultrasound examination, laparoscopic cholecystectomy

Abstract

In the structure of emergency surgical care, acute calculous cholecystitis takes the second place, ahead of acute appendicitis and second only to acute pancreatitis. And therefore, the search and development of optimal approaches to the diagnosis and surgical treatment of acute calculous cholecystitis continues, with the development and improvement of the relevant recommendations and guidelines.

Aim - to assess the place and role of preoperative ultrasound examination in the diagnosis of acute calculous cholecystitis and predicting the results of early laparoscopic cholecystectomy.

Materials and methods. A retrospective analysis of the treatment of 685 patients with uncomplicated acute calculous cholecystitis during 2021-2024 was conducted. The location of the gallbladder, its size, thickness and condition of the walls, the nature of the contents, the presence of calculi in the gallbladder cavity and their mobility, the condition of the extrahepatic bile ducts, the presence or absence of infiltrates and fluid formations near the gallbladder were assessed. Statistical processing was performed using the statistical software package (SPSS) 20.0 for Windows.

Results. The main method of visualization of acute calculous cholecystitis was ultrasound, which was performed in 100% of patients, which allowed in most cases (93.8%), to diagnose the disease with its sonographic characteristics. Among the ultrasound symptoms that highest predict difficult laparoscopic surgery were: gallstone disease, thickened gallbladder wall, gallbladder neck stone and presence of pericholecystic fluid. They can be used in predicting the need for open surgery, as they are indicators of the fact that laparoscopy can be significantly complicated due to the development of an inflammatory-destructive process.

Conclusions. Ultrasound is a simple, non-invasive, widely available and highly informative method of the first line of visualization of acute calculous cholecystitis, which in 93.8% of cases allows to confirm the diagnosis with a general sensitivity of 93.4% and specificity of 82.3%. The presence of three or more ultrasound symptoms of acute calculous cholecystitis has almost 100% informativeness in its diagnosis.

The study was conducted in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethics Committee of the institution mentioned in the paper. Informed consent of patients was obtained for the study.

The authors declare no conflict of interest.

References

Ahmed TA, Sultan AJ, Najla MY, Albatoul AA, Azzam KA et al. (2024, Oct 22). Impact of Surgical Timing on Outcomes in Patients With Acute Cholecystitis: A Systematic Review. Cureus. 16(10): e72090. https://doi.org/10.7759/cureus.72090

Altıner S, Ergüder E, Altınok SH, Aydın SM, Barlas AM, Tuncal S. (2023, Oct). The role of preoperative ultrasound in predicting conversion from laparoscopic cholecystectomy to open surgery in acute cholecystitis. Ulus Travma Acil Cerrahi Derg. 29(10): 1109-1113. https://doi.org/10.14744/tjtes.2023.45469; PMid:37791445 PMCid:PMC10644075

Gallaher Jared R, Charles A. (2022, Mar 8). Acute Cholecystitis: A Review. JAMA. 327(10): 965-975. https://doi.org/10.1001/jama.2022.2350; PMid:35258527

Hiatt KD, Ou JJ, Childs DD. (2020). Role of Ultrasound and CT in the Workup of Right Upper Quadrant Pain in Adults in the Emergency Department: A Retrospective Review of More Than 2800 Cases. Am. J. of Roentgenoljgy. 214(6). https://doi.org/10.2214/AJR.19.22188; PMid:32160055

Huang SS, Lin KW, Liu KL, Wu YM, Lien WC, Wang HP. (2023, Nov 30). Diagnostic performance of ultrasound in acute cholecystitis: a systematic review and meta-analysis. World J Emerg Surg. 18(1): 54. https://doi.org/10.1186/s13017-023-00524-5; PMid:38037062 PMCid:PMC10687940

Kim HY, Lee JH, Kim SG, Lee SH, Paik S, Kim HJ et al. (2025, Feb). Ultrasonographic predictors of acute gangrenous cholecystitis in patients treated with laparoscopic cholecystectomy: a single center retrospective study. Scand J Gastroenterol. 60(2): 174-183. Epub 2024 Dec 31. https://doi.org/10.1080/00365521.2024.2447525; PMid:39902898

Mahmoudzadeh F, Akhgar A, Mirfazaelian H. (2024, Jan 26). External validation of the bedside score for the diagnosis of acute cholecystitis. Heliyon. 10(3): e25183. https://doi.org/10.1016/j.heliyon.2024.e25183; PMid:38322927 PMCid:PMC10844041

Martínek L, Hoch J. (2024). Early cholecystectomy. Rozhl Chir. 103(8): 294-298. https://doi.org/10.48095/ccrvch2024294; PMid:39313357

Masamichi Y, Tadahiro T, Steven MS, Joseph SS, Toshihiko M et al. (2013). TG13 diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 20: 35-46. https://doi.org/10.1007/s00534-012-0568-9; PMid:23340953

Mencarini L, Vestito A, Zagari RM, Montagnani M. (2024). New Developments in the Ultrasonography Diagnosis of Gallbladder Diseases. Gastroenterology Insights. 15(1): 42-68. https://doi.org/10.3390/gastroent15010004

Navarro SM, Chen S, Situ X, Corwin MT, Loehfelm T, Fananapazir G. (2023, Jun). Sonographic Assessment of Acute Versus Chronic Cholecystitis: An Ultrasound Probability Stratification Model. J Ultrasound Med. 42(6): 1257-1265. https://doi.org/10.1002/jum.16138; PMid:36457230 PMCid:PMC10191874

Nugent JP, Li J, Pang E, Harris A. (2023, Jan). What's new in the hot gallbladder: the evolving radiologic diagnosis and management of acute cholecystitis. Abdom Radiol (NY). 48(1): 31-46. Epub 2022 Mar 1. https://doi.org/10.1007/s00261-022-03451-2; PMid:35230497

Okamoto K, Suzuki K, Takada T, Strasberg SM, Asbun HJ et al. (2018, Jan). Tokyo Guidelines 2018: flowchart for the management of acute cholecystitis. J Hepatobiliary Pancreat Sci. 25(1): 55-72. https://doi.org/10.1002/jhbp.516; PMid:29045062

Pisano M, Allievi N, Gurusami K, Borzellino G, Cimbanassi S, Boerna D et al. (2020, Nov 5). 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis. World J Emerg Surg. 15(1): 61. https://doi.org/10.1186/s13017-020-00336-x; PMid:33153472 PMCid:PMC7643471

Pisano M, Ceresoli M, Cimbanassi S, Gurusamy K, Coccolini F et al. (2019, Mar 4). 2017 WSES and SICG guidelines on acute calcolous cholecystitis in elderly population. World J Emerg Surg. 14: 10. https://doi.org/10.1186/s13017-019-0224-7; PMid:30867674 PMCid:PMC6399945

Ramia JM, Serradilla-Martín M, Villodre C, Rubio JJ, Rotellar F, Siriwardena AK et al. (2024, Oct 12). International Delphi consensus on the management of percutaneous choleystostomy in acute cholecystitis (E-AHPBA, ANS, WSES societies). World J Emerg Surg. 19(1): 32. https://doi.org/10.1186/s13017-024-00561-8; PMid:39396036 PMCid:PMC11470677

Shaish H, Ma HY, Ahmed FS. (2021, Jun). The utility of an under-distended gallbladder on ultrasound in ruling out acute cholecystitis. Abdom Radiol (NY). 46(6): 2498-2504. Epub 2021 Jan 2. https://doi.org/10.1007/s00261-020-02902-y; PMid:33386917

Schuster KM, Schroeppel TJ, O'Connor R, Enniss TM, Cripps M et al. (2023, Jul). Imaging acute cholecystitis, one test is enough. Am J Surg. 226(1): 99-103. https://doi.org/10.1016/j.amjsurg.2023.02.018; PMid:36882336

Tse JR, Gologorsky R, Shen L, Bingham DB, Jeffrey RB, Kamaya A. (2022, Mar). Evaluation of early sonographic predictors of gangrenous cholecystitis: mucosal discontinuity and echogenic pericholecystic fat. Abdom Radiol (NY). 47(3): 1061-1070. Epub 2022 Jan 5. https://doi.org/10.1007/s00261-021-03320-4; PMid:34985635

Wael M, Seif M, Mourad M, Altabbaa H, Ibrahim IM, Elkeleny MR. (2024, Dec). Early Versus Delayed Laparoscopic Cholecystectomy, after Percutaneous Gall Bladder Drainage, for Grade II Acute Cholecystitis TG18 in Patients with Concomitant Cardiopulmonary Disease. J Laparoendosc Adv Surg Tech A. 34(12): 1069-1078. https://doi.org/10.1089/lap.2024.0233; PMid:39234751

Yokoe M, Hata J, Takada T, Strasberg SM, Asbun HJ et al. (2018). Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 25(1): 41-54. https://doi.org/10.1002/jhbp.515; PMid:29032636

Published

2025-09-28

Issue

Section

Original articles. Abdominal surgery