First experience of implantation of diaphragm pacemakers in infant with bilateral diaphragmatic paralysis

Authors

DOI:

https://doi.org/10.15574/PS.2023.78.127

Keywords:

newborn, bilateral diaphragmatic paralysis, treatment

Abstract

Phrenic nerve injury is not frequent, but well recognized complication of birth trauma caused by brachial plexus injury. Diaphragmatic paresis is usually unilateral, and cases of bilateral damage are rare. Diaphragmatic paralysis led to development of severe respiratory disorders, which required the prolonged intensive care, often with the applying of mechanical ventilation. Although is it possible the spontaneous restoration the function of the diaphragm, this requires the long-term of respiratory support. The general accepted guidelines of the treatment of infants with paresis/paralysis of diaphragm is absent. Diaphragmatic plication considered as the main surgical method of treatment. By that, diaphragmatic plication not always had a positive effect.

The aim of the study was to present new possibility in the treatment of infants with bilateral diaphragmatic paralysis.

Clinical case. We presented the first experience of transthoracic implantation of diaphragm pacemaker in infant with bilateral diaphragmatic paralysis.

The newborn was hospitalized with the respiratory disorders’ syndrome. The paresis of both hemidiaphragms was reviled on chest X-ray. For 7 months child required the mechanical ventilation, due to unsuccessful attempts to transfer the child to spontaneous breathing caused the decrease of saturation. With the aim to restore spontaneous breathing, the implantation of diaphragm pacemaker, under the thoracoscopic control, was performed initially at the right side and next at the left side. The effectiveness of the treatment was confirmed by the electroneuromyography and ultrasonography.

Conclusions. Implantation of the diaphragmatic pacemaker my be the method of treatment in infants with bilateral diaphragmatic paralysis.

The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies.

No conflict of interests was declared by the authors.

References

Aldrich TK, Herman JH, Rochester DF. (1980). Bilateral diaphragmatic paralysis in the newborn infant. J Pediatr. 97 (6): 988-991. https://doi.org/10.1016/S0022-3476(80)80442-2; PMid:7441433

Bhaskar P, Lone RA, Sallehuddin A et al. (2016). Bilateral diaphragmatic palsy after congenital heart surgery: management options. Cardiol Young. 26 (5): 927-930. https://doi.org/10.1017/S1047951115001559; PMid:26345716

Bowerson M, Nelson VS, Yang LJ. (2010). Diaphragmatic paralysis associated with neonatal brachial plexus palsy. Pediatr Neurol. 42 (3): 234-236. https://doi.org/10.1016/j.pediatrneurol.2009.11.005; PMid:20159438

Commare MC, Kurstjens SP, Barois A. (1994). Diaphragmatic paralysis in children: a review of 11 cases. Pediatr Pulmonol. 18 (3): 187-193. https://doi.org/10.1002/ppul.1950180311; PMid:7800436

Dagan O, Nimri R, Katz Y et al. (2006). Bilateral diaphragm paralysis following cardiac surgery in children: 10-years' experience. Intensive Care Med. 32 (8): 1222-1226. https://doi.org/10.1007/s00134-006-0207-5; PMid:16741697

Gibson GJ. (1989). Diaphragmatic paresis: pathophysiology, clinical features, and investigation. Thorax. 44 (11): 960-970. https://doi.org/10.1136/thx.44.11.960; PMid:2688182 PMCid:PMC462156

Hoeksma AF, ter Steeg AM, Nelissen RGHH et al. (2004). Neurological recovery in obstetric brachial plexus injuries: an historical cohort study. Dev Med Child Neurol. 46 (2): 76-83. https://doi.org/10.1111/j.1469-8749.2004.tb00455.x

Joho-Arreola AL, Bauersfeld U, Stauffer UG et al. (2005). Incidence and treatment of diaphragmatic paralysis after cardiac surgery in children. Eur J Cardiothorac Surg. 27 (1): 53-57. https://doi.org/10.1016/j.ejcts.2004.10.002; PMid:15621471

Kraaijenga JV, Hutten GJ, de Jongh FH, van Kaam AH. (2015). Diagnosis of hemidiaphragmatic paresis in a preterm infant with transcutaneous electromyography: A case report. Neonatology. 108 (1): 38-41. https://doi.org/10.1159/000381207; PMid:25968010

Muller NL, Bryan AC. (1979). Chest wall mechanics and respiratory muscles in infants. Pediatr Clin North Am. 26 (3): 503-516. https://doi.org/10.1016/S0031-3955(16)33745-2; PMid:386235

Murty VSSY, Ram KD. (2012). Phrenic nerve palsy: a rare cause of respiratory distress in newborn. J Pediatr Neurosci. 7 (3): 225-227. https://doi.org/10.4103/1817-1745.106487; PMid:23560016 PMCid:PMC3611918

Qureshi A. (2009). Diaphragm paralysis. Semin Respir Crit Care Med. 30 (3): 315-320. https://doi.org/10.1055/s-0029-1222445; PMid:19452391

Radecki LL, Tomatis LA. (1976). Continuous bilateral electrophrenic pacing in an infant with total diaphragmatic paralysis. J Pediatr. 88 (6): 969-971. https://doi.org/10.1016/S0022-3476(76)81051-7; PMid:1083902

Rizeq YK, Many BT, Vacek JC et al. (2020). Diaphragmatic paralysis after phrenic nerve injury in newborns. Pediatr Surg. 55 (2): 240-244. https://doi.org/10.1016/j.jpedsurg.2019.10.038; PMid:31757507

Shimizu M. (2003). Bilateral phrenic-nerve paralysis treated by thoracoscopic diaphragmatic plication in a neonate. Pediatr Surg Int. 19 (1-2): 79-81. https://doi.org/10.1007/s00383-002-0737-z; PMid:12721731

Shiohama T, Fujii K, Hayashi M et al. (2013). Phrenic nerve palsy associated with birth trauma - case reports and a literature review. Brain Dev. 35 (4): 363-366. https://doi.org/10.1016/j.braindev.2012.06.002; PMid:22742777

Stramrood CA, Blok CA, van der Zee DC, Gerards LJ. (2009). Neonatal phrenic nerve injury due to traumatic delivery. J Perinat Med. 37 (3): 293-296. https://doi.org/10.1515/JPM.2009.040; PMid:19199838

Van Smith C, Jacobs JP, Burke RP. (1998). Minimally invasive diaphragm plication in an infant. Ann Thorac Surg. 65 (3): 842-844. https://doi.org/10.1016/S0003-4975(98)00008-3; PMid:9527232

Published

2023-03-28